By Peter McLaughlin, Lester E. Robertson, Michael J. Keating (auth.), Fernando Cabanillas M.D., M. Alma Rodriguez M.D. (eds.)
Fernando Cabanillas In 1993, Fisher et al. released the result of a randomized trial evaluating 3 third-generation regimens opposed to the vintage CHOP mixture. For numerous years, the oncology neighborhood have been confident that the 3rd new release regimens have been sincerely more advantageous to cut. It got here as a surprise to many who there has been no distinction in consequence among the 4 fingers of this scientific trial. The logical end is that CHOP is nearly as good as any of the opposite regimens validated in that learn. regrettably, this wonderful learn has been misinterpreted through many as proving that there has now not been any growth within the box of lymphoma over the last two decades. additionally, it has resulted in a fatalistic perspective within the reasoning of many clinicians who suppose that 'nothing works greater than CHOP' and consequently that it isn't worthy trying out new medicinal drugs or constructing novel regimens. notwithstanding, the method during which we flow ahead within the oncology box is seldom by means of dramatic breakthroughs. usually, what seems initially look to be a leap forward seems later to be only a modest breakthrough. numerous steps ahead ultimately upload as much as a huge enhance, yet this improve is going left out as a result of sluggish nature of the method. during this quantity, we've got selected to debate numerous of those steps, which we suppose are basically creating a confident impression at the box of lymphomas and which quickly should still make an important distinction in healing results.
Read Online or Download Advances in Lymphoma Research PDF
Similar research books
Fabrication applied sciences for nanostructured units have be- en constructed lately, and and optical professional- perties of such nanostructures are an issue of complicated re- seek. This ebook describes the several methods to spectroscopic microscopy, i. e. , electron beam probe spec- troscopy, spectroscopic photoelectron microscopy, and experiment- ning probe spectroscopy.
Realizing schooling study is designed to aid scholars learn how to learn academic study articles conscientiously, systematically, and severely. scholars discover ways to categorize titles, decode abstracts, locate study questions, signify examine arguments, holiday down equipment and techniques, discover references, observe research thoughts, and interpret findings.
- Social Research in Bethnal Green: An evaluation of the work of the Institute of Community Studies
- The Access Principle: The Case for Open Access to Research and Scholarship (Digital Libraries and Electronic Publishing)
- Carbon Monoxide Poisoning [Prog. in Brain Research Vol 24]
- The Students' Guide to Research Ethics
- Progress in Electrodermal Research
- Riverbank Filtration Hydrology: Proceedings of the NATO Advanced Research Workshop on Riverbank Filtration Hydrology Bratislava, Slovakia September 2004
Extra info for Advances in Lymphoma Research
Hickish T, Serafinowski P, Cunningham D, et al. (1993). 2-Chlorodeoxyadenosine: evaluation of a novel predominantly lymphocyte selective agent in lymphoid malignancies. Br J Cancer 67:139-143. 11. Saren A, Emanuele S, Kosty M, Koziol J, Ellison D, Piro L (1995). 2 chlorodeoxyadenosine activity in untreated, indolent non-Hodgkin's lymphoma. Blood 86:1710-1716. 11a. Piro LD, Petroni G, Barcos M, Johnson J, Saven A, Peterson B (1995). Bolus infusion of 2chlorodeoxyadenosine (2-CdA) as first-line therapy of low grade non-Hodgkin's lymphoma (NHL): CALGB 9153.
This entity was not recognized in the Working Formulation for Clinical Usage, and its description caused controversy among Fernando Cabanillas and M. Alma Rodriguez (eds), ADVANCES IN LYMPHOMA RESEARCH. Copyright © 1997. Kluwer Academic Publishers, Boston. All rights reserved. pathologists and confusion among clinicians . Several years later, Weisenberger identified a distinctive type of follicular lymphoma that he called mantle zone lymphoma (MZL), due to the distinctive pattern exhibited by the malignant cells growing in wide mantles around benign germinal centers .
Carson DA, Kaye J, Seegmiller JE (1978). Differential sensitivity of human leukemic T cell lines and B cell lines to growth inhibition by deoxyadenosine. J ImmunoI121:1726-1731. 20. Carson DA, Wasson DB, Kaye J, et al. (1980). Deoxycytidine kinase-mediated toxicity of deoxyadenosine analogs towards malignant human lymphoblasts in vitro and toward murine L1210 leukemia in vivo. Proc Nat! Acad Sci USA 77:6865-6869. 21. Avery T, Rehg J, Lumm W, Harwood FC, Santana VM, Blackley RL (1989). Biochemical pharmacology of 2-chlorodeoxyadenosine in malignant human hematopoietic cell lines and therapeutic effects of 2-bromodeoxyadenosine in drug combinations in mice.
Advances in Lymphoma Research by Peter McLaughlin, Lester E. Robertson, Michael J. Keating (auth.), Fernando Cabanillas M.D., M. Alma Rodriguez M.D. (eds.)